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Training to failure or stopping short: what the science says about reps in reserve

The "no pain no gain" culture says go to total failure on every set. Recent strength research says stopping one to three repetitions short delivers nearly the same muscle, with less fatigue and less risk. See both sides and what the best evidence really shows.

Barbell squat in a dark gym, amber light
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0.19 Standardized difference (trivial effect) in favor of failure for hypertrophy, 95% CI 0.00 to 0.37 Refalo et al., 2022, Sports Medicine
0.181 vs 0.182 cm Quadriceps thickness gain: failure vs. reps in reserve, after 8 weeks Refalo et al., 2024, Journal of Sports Sciences
~0 Relationship between proximity to failure and strength gain (confidence interval crosses zero) Robinson, Pelland, Refalo et al., 2024, Sports Medicine

The controversy in one sentence

There is an old dogma in the weight room: if the last repetition did not grind to a halt on its own, you left muscle on the table. Taking every set to momentary muscular failure, the point where the weight simply will not go up anymore, became synonymous with real effort. On the other side, a wave of studies from 2022 to 2025 suggests something uncomfortable for those raised in that culture: stopping a little earlier, leaving reps in reserve (RIR, from reps in reserve), delivers practically the same result with much less wear. Who is right?

The "go to failure" side

The argument is intuitive and has partial physiological support. Failure guarantees you recruited the highest-threshold motor units, the fibers most associated with growth, and removes the doubt about "did I go too light?". A set taken to the limit leaves no room for self-deception when estimating effort.

And the evidence is not zero. A systematic review with meta-analysis found an advantage in favor of training to failure for hypertrophy. The problem, as you will see, is the size of that advantage.

Failure vs. non-failure for hypertrophy: standardized difference of means of 0.19 (95% CI: 0.00 to 0.37; p = 0.045), classified by the authors themselves as a trivial effect. In the subgroup that specifically compared momentary muscular failure, the difference fell to 0.12 (95% CI: minus 0.13 to 0.37) and was no longer statistically significant. Refalo et al., 2022, Sports Medicine (15 studies)

The "leave reps in reserve" side

Here lies the turn. If failure's advantage is trivial for muscle size, its cost is not: going to the limit on every set generates much more fatigue, requires more recovery time and increases the risk of technical failure, when form breaks before the muscle does. That reduces how much quality volume you can accumulate over the week, and weekly volume is one of the most robust drivers of hypertrophy.

The most elegant test came from a study with a within-subject design, in which each person trained one leg to failure and the other stopping with 1 to 2 repetitions in reserve. After eight weeks, the two legs grew practically the same.

Quadriceps thickness after 8 weeks: 0.181 cm on the side that went to failure vs. 0.182 cm on the side that stopped with reps in reserve. Essentially identical gain, with 18 trained participants (12 men, 6 women). Refalo et al., 2024, Journal of Sports Sciences

What the best evidence says

The most complete reading to date came from a series of meta-regressions that, instead of treating the subject as a switch (failure yes or no), modeled proximity to failure as a continuum, repetition by repetition in reserve. And the result separated two outcomes that gym culture tends to mix up.

  • For hypertrophy: the closer to failure, a little more growth. The advantage exists, but it is modest.
  • For strength: proximity to failure practically changes nothing. Leaving repetitions in reserve ties with going to failure, and the clean technique that remains tends to help.
In the meta-regressions, the slope for hypertrophy was negative and significant (fewer reps in reserve, more muscle), while for strength the confidence intervals crossed zero, indicating a negligible relationship. Robinson, Pelland, Remmert, Refalo, Jukic, Steele, Zourdos, 2024, Sports Medicine

Translating to the bar: if your goal is strength, there is no reason to chase failure, and there are good reasons to avoid it (recovery, technical consistency, joint longevity). If the goal is size, training close to failure on most sets captures nearly all the benefit. Total failure becomes an occasional tool, useful on the last set of a simple, safe exercise, not a tax collected on every repetition.

It is worth noting who was already operating this way long before the headlines. RPE-based autoregulation systems used by elite lifters, such as Mike Tuchscherer's, anchor each set precisely on repetitions in reserve and avoid failure by default, because what you gain by going to the limit does not compensate for how much less recovered you are for the next session.

The honest verdict

Failure is not forbidden or useless. It is an expensive tool. The current evidence points to a middle path that "no pain no gain" culture never offered: work close to failure, not always at it. For most trained people, stopping with 1 to 3 repetitions in reserve preserves technical quality, allows more volume over the week and delivers comparable growth, without the recovery hole that constant failure opens.

This content is educational and does not replace individualized professional evaluation. The ideal proximity to failure varies with the exercise, injury history and goal. Load, volume and technique adjustments should be supervised by an exercise professional.

Who proves it in practice

Mike Tuchscherer Champion powerlifter and creator of Reactive Training Systems

Gold medalist at the 2009 World Games (first US male for USAPL) and world record holder in the 120 kg class. He popularized RPE-based autoregulation anchored on reps in reserve; his method avoids failure by default because it leaves the athlete less recovered without proportional gain.

Dr. Mike Israetel PhD in sport physiology, cofounder of Renaissance Periodization

He recommends training within a window of approximately 3 to 1 reps in reserve for hypertrophy and using total failure (0 RIR) only occasionally, to control fatigue accumulation.

Participants of the Refalo study (2024) 18 trained adults (12 men, 6 women), Journal of Sports Sciences

In an within-subject design, they grew practically the same in both legs: 0.181 cm of quadriceps thickness in the to-failure leg vs. 0.182 cm in the reps-in-reserve leg, after 8 weeks.

Answers about the topic

Frequently asked questions

Strength

Do I need to train to failure to gain muscle?

No. The best evidence shows that training close to failure, leaving 1 to 3 repetitions in reserve, delivers practically the same growth as going to total failure, with far less fatigue. Failure's advantage for hypertrophy is modest and, for strength, negligible.

What does leaving reps in reserve (RIR) mean?

It means stopping the set before absolute failure, keeping an estimated number of repetitions you could still do. For example, 2 RIR means ending the set when you could still do two more repetitions with good form. Many athletes use the RPE scale, where RPE 8 equals 2 repetitions in reserve and RPE 7 equals 3 repetitions in reserve.

So failure never serves any purpose?

It does, but as an occasional tool. Failure helps confirm effort and can be useful on the last set of a simple, safe exercise, or on isolation machines. The problem is using it on every set, because it costs recovery, hurts technique and limits the quality volume you accumulate over the week.

Does anything change if my goal is strength and not size?

A lot changes. In the 2024 meta-regressions, proximity to failure practically did not affect strength gains (the confidence interval crossed zero). For strength, leaving repetitions in reserve ties with going to failure and still preserves technique and joints, so chasing failure makes no sense.

How many reps in reserve should I leave in practice?

A range of 1 to 3 repetitions in reserve on most sets usually captures nearly all the benefit, both for hypertrophy and strength. Save total failure for specific cases and adjust according to the exercise, your injury history and how much you recover between sessions, preferably with professional supervision.

References

  1. Refalo MC, Helms ER, Trexler ET, Hamilton DL, Fyfe JJ (2022). Influence of Resistance Training Proximity-to-Failure on Skeletal Muscle Hypertrophy: A Systematic Review with Meta-analysis. Sports Medicine.
  2. Robinson ZP, Pelland JC, Remmert JF, Refalo MC, Jukic I, Steele J, Zourdos MC (2024). Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions. Sports Medicine, 54(9), 2209-2231.
  3. Refalo MC, Helms ER, Robinson ZP, Hamilton DL, Fyfe JJ (2024). Similar muscle hypertrophy following eight weeks of resistance training to momentary muscular failure or with repetitions-in-reserve in resistance-trained individuals. Journal of Sports Sciences, 42(1).
  4. Robinson ZP et al. (preprint). Exploring the Dose-Response Relationship Between Estimated Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions. SportRxiv.
  5. Reactive Training Systems (Mike Tuchscherer): RPE autoregulation and reps in reserve.

Educational content. It does not replace a consultation with a dietitian or a physician. An individualized meal plan is an act reserved to licensed dietitians under Brazilian law (Lei 8.234/91). Sources are cited with a link for verification. Images under the Unsplash License (free use, including commercial).